I wouldn't recommend seeing this movie in IMAX. The effects would be just as stunning in regular size (IMAX seems like it's about a third bigger to my eye) and you would emerge with your hearing intact.
That said, the movie is very engrossing while you're watching, offering multiple layers of intrigue, crazy eye candy, and enough ambiguity to make for a long conversation on the ride home.
I would say it seemed like a pretty similar film to "Memento," which I much preferred. But given that "Memento" is one of my favorite movies, I did really enjoy watching a $150 million dollar riff on the same themes.