First off, I am biased in that I have loved the RE movies since the first one. I love the whole evil Umbrella Corp thing.
This movie brought back some old friends in new roles. It put in some new twists and helped evolve the RE storyline. It is amazing to me that they can pump out these RE movies and not make the storylines tired or forced. This movie's story melded with the earlier ones and evolved it in a new direction. Clearly leaving room for more as it seems every movie does now a days, I eagerly await the next installment of RE. This one will wind up on the movie rack next to the others when it comes out on video.