This was one of the best movies I've seen in a very long time. This family's struggles with not one, but two children afflicted with a devastating disease are all very real. This father's determination to bring to market a medication that could potentially help them - and other children like them - is inspiring and is an example to others that one person, one family, can make a difference. What was glossed over some was the struggle that, I'm sure, the research company faced getting the FDA to approve the medication for test-marketing. Casting was *excellent*!!!