Though many of my friends have refused to see this movie because it is "depressing," I thought it was absolutely phenomenal. "UP" is Pixar's best movie to date. Not just visually beautiful, the story is concise and unimaginably moving emotionally. And oh yeah, it's really funny too.
Accompanied by a sweepingly romantic musical score, you will quite figuratively be swept off your feet. A strong contender for Best Score and almost sure-fire nominee for Best Picture (especially since the Academy is nominating ten films this year).