Strengths: Nice looking, especially considering lack of cooperation from the Catholic church who is so central to the film.
Weaknesses: Acting is not memorable. But that's far from the biggest problem. The burdensome explanations required have characters saying things they would never need to say. Everything moves way too fast: Hanks' professor is viewed suspiciously in the morning due to his prior work, but by that evening they trust him with their lives. The "anti-matter" explosion is described as being something completely devestating, on the order of a nuclear bomb, yet it air-bursts no more than 10-15,000 feet over St. Peter's square, and nobody appears to be killed.